The study found that mutations to VPS35, a key player in this pathway, can prevent chemotherapy-induced cell death. These results, published in Nature, could help pinpoint treatment-resistant tumors.

New Delhi, March 29 (IANS): US researchers have found how resistance to chemotherapies may occur in some cancers, an advance ...

A phase 3 trial of nemvaleukin alfa in with Keytruda for patients with platinum-resistant ovarian cancer will not continue on ...

A new drug combination from Corcept Therapeutics, relacorilant, has shown potential in treating platinum-resistant ovarian ...

One study showed small cell lung cancer (SCLC) tumors with higher DNA damage response (DDR) activity were initially more ...

The Company expects to submit a New Drug Application to the Food and Drug Administration in the third quarter of 2025.

Mirvetuximab soravtansine improved overall survival, progression-free survival, second progression-free survival, and other outcomes.

Investigators have uncovered how resistance to chemotherapies may occur in some cancers. Researchers focused on a pathway that harnesses reactive oxygen species (ROS) to kill cancer cells. The study ...