Researchers investigating the role of the protein CD44 in obesity and metabolic health found that CD44-deficient mice stayed lean even on a high-fat diet, while the control mice developed obesity.
Blocking a protein called CD44 has been shown to protect against obesity in mice on a high-fat diet, specifically by suppressing the formation of white fat cells.
In experiments conducted at the University of São Paulo, tumor stem cells became less able to proliferate and invade tissues ...
SPP1+ Macrophages Identified as Key Drivers and Therapeutic Targets In Colorectal Cancer Progression
Colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related deaths worldwide.
Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related mortality worldwide. Current treatment modalities are few or ...
The expression of cancer stemness markers, like CD44, MET, CD133, FUT4, ACVR1, mTOR, and KLF4 correlated positively with IARS2 expression, suggesting that IARS2 promotes metastasis via regulation ...
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