The use of an investigational topical BRAF-inhibiting gel appeared to be effective in treating acneiform rash in patients ...

Toasted skin syndrome refers to a type of rash some people develop from heat sources such as laptops, space heaters, or ...

LUT014, a BRAF inhibitor gel, improved acne-like rashes in patients with colorectal cancer undergoing anti-EGFR therapy, ...

Researchers from the UCLA Health Jonsson Comprehensive Cancer Center and The University of Texas MD Anderson Cancer Center ...

LUT014 works by paradoxically reactivating MAPK, a key signaling pathway in the skin that anti-EGFR therapies shut down.

Novel treatment allowed patients with colorectal cancer to successfully continue taking their cancer treatment with improved quality of life. Acne-like skin rash is a common side effect from ...

Topical BRAF inhibitor LUT014 gel significantly reduces acneiform rash from anti-EGFR therapies in patients with colorectal ...

A new topical gel called LUT014 successfully reduced the severity of a painful acne‐like rash that commonly occurs as a side effect of targeted therapy with epidermal growth factor receptor (EGFR) ...

For 40 patients who received the low-dose 0.03% LUT014 formulation, the treatment ... skin and reduce the severity of the rash. This study included 118 patients with metastatic colorectal cancer ...