(D) Immunofluorescence co-staining of CD4 (red), CD45RO (green) and DAPI (blue) in frozen placental sections. The right panels show the fluorescence intensity of CD4 and CD45RO.Scale bar, 20 µm. (E) ...
Cells were fixed and surface stained with fluorochrome-conjugated antibodies specific for human CD3, CD4, CD8, CD45RO, CD56, CD127, CCR6, HLA-DR, γδTCR (all from BD Biosciences), V α 24 J α 18 TCR ...
IL-18-primed NK cells recruit dendritic cells and potentiate tumor therapy mediated by PD-1 blockade
The success of cancer immunotherapy depends on the effective coordination of innate and adaptive immunity. We previously reported that IL-18 potentiates the therapeutic effects of immune checkpoint ...
Objective: Although photodynamic therapy (PDT) has been proven effective in various tumors, it has not been widely used as a routine treatment for colorectal cancer (CRC), and the characteristics of ...
BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...
Interleukin 15 expression in asthmatic airways negatively correlated with lung function, a finding that improves ...
This important study utilizes humanized mice, in which human immune cells are introduced into immune-deficient mice, to provide convincing evidence that two helper CD4 T-cell subsets, T-follicular ...
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