However, on the other hand, they favoured recruitment of beneficial neutrophils through IL-8 secretion and, most importantly, they drove highly cytotoxic CCR5+CCR6+CD8+ T cells into tumour tissue, ...
Importantly, these tumours overexpress CCL5 and have enhanced CD8+T cell infiltration. Complementary mechanisms, such as hypermethylation of antigen-presenting genes, may contribute to these ...
Z-scores for each timepoint are shown for IL-13, IL-4, IL-8, LIF, CCL1, CCL5, CCL7, and CCL8 (Figure 5). Upon IL-33 treatment, CCL1, LIF, CCL7, and CCL5 were all significantly upregulated after IL-33 ...
regulated upon activation normal T cell expressed and presumably secreted (RANTES)/CCL5, tumor necrosis factor-α (TNF-α), and vascular endothelial growth factor A (VEGF-A). Measurements were performed ...
BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...
Expert Rev Clin Immunol. 2013;9(3):211-216. Atopic dermatitis is a chronic inflammatory skin disease that commonly begins in early infancy, runs a course of exacerbations and remissions and is ...
Herpesvirus-encoded microRNAs (v-miRNAs) play a crucial role in modulating host cellular processes to promote viral persistence, immune evasion, and pathogenesis. These v-miRNAs function by targeting ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The Cancer Genome Explorer (TCGEx) is a ...