Densitometry was performed with Image J and the result for each protein of interest was normalized by its corresponding GAPDH blot and presented in the bar graph. Values are the Mean +/- SEM for each ...

This study presents an important finding on the alterations in the autophagic-lysosomal pathway in a Huntington's disease model ... and the result is shown in the bar graph. Statistical significances ...

It is well understood that the neurodegenerative disorder Huntington’s disease is caused by an N-terminal polyQ-expansion (>35) in the Huntingtin (HTT) gene. This mutation leads to axonal ...

A decade ago, University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington's disease? They found that ...

The number of people who have the gene that causes Huntington's disease in Northern Scotland has been accurately counted for the first time in 35 years in new research from the University of ...

CHARLESTON, S.C. (WCIV) — The South Carolina Chapter of the Huntington’s Disease Society of America is set to host a Team Hope Walk, with the goal of raising money to help improve the lives of ...

They found that two specific signaling proteins, GSK3ß and ERK1, were expressed more in the neurons of Huntington’s disease patients, so they prevented them from functioning in the neurons of ...

BUFFALO, N.Y. — A decade ago, University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington’s disease?

From reproductive rights to climate change to Big Tech, The Independent is on the ground when the story is developing. Whether it's investigating the financials of Elon Musk's pro-Trump PAC or ...

High dose and low dose AMT-130 demonstrated an 80% and 30% slowing of disease progression vs external control, respectively. The Food and Drug Administration has granted Breakthrough Therapy ...

Northern Scotland has one of the highest rates of Huntington’s disease in the world, a study has found. The number of people living in the area who have the gene that causes the condition has ...

A decade ago, University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington's disease? They found that ...