This study provides a potentially useful investigation into the positive role of BDNF/TrkB signaling in implanted dental pulp stem cells to enhance dentin regeneration in the context of dental caries.

BTM-3566 is a first-in-class, small molecule cancer therapeutic which targets mitochondrial homeostasis via the ATF4-Integrated Stress Response (ISR) pathway to treat aggressive tumors. “Activating ...

Diabetic kidney disease (DKD) is a prevalent complication of diabetes mellitus (DM), and its incidence is increasing alongside the number of diabetes cases. Effective treatment and long-term ...

This phosphorylation has a dual effect: it reduces overall protein synthesis, lessening the burden on the ER, and it selectively increases the translation of certain mRNAs, including ATF4, which ...

Comparison of laparoscopic radiofrequency ablation with percutaneous radiofrequency ablation in the treatment of chronic hepatitis B-related hepatocellular carcinoma involving specific sites: A ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Purified FICD and BiP protein concentrations were measured ...

This cover highlights the article Multimodal mechanisms of human centriole engagement and disengagement by Kei K. Ito, Shoji Hata, Daiju Kitagawa and colleagues. The cover image depicts the centriole ...

Objective Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor expressed in tissues with high oxidative activity that plays a central role in metabolism. In this work, we ...

Correspondence to Professor Peter A B Wark, Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Medicine and Public Health, The University of Newcastle, ...

Department of Nuclear Medicine, Xinqiao Hospital, Army Medical University, Chongqing 400037, China School of Medical Imaging, North Sichuan Medical College, NanChong 637100, China Department of ...