An imbalance in ligands, which are molecules produced by the body and the gut microbiota, can affect a key receptor protein ...

The reaction can also handle coupling partners that don’t work as well with other cross-couplings, such as nitrogen-containing rings. And it works with anilines and aryl boronates, which can be used ...

PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...

Innovative glass functionalization via ultrasonication creates stable Si–O–C bonds, addressing traditional method limitations ...

Breakthrough in N2 activation! This study unveils an electron catalysis strategy that directly converts N2 into azo compounds under mild conditions—a game-changer for nitrogen fixation. By harnessing ...

Legislators who are not term-limited and still have surpluses in the six-figure range are Sens. Jarrett Keohokalole, Troy ...

Organon has shared positive results from a long-term extension (LTE) study of its Vtama (tapinarof) cream, 1% in atopic dermatitis (AD) patients aged as young as two years.

This highlight describes a series of novel 6-aryl isoindolin-1-one derivatives as negative allosteric modulators (NAMs) of the metabotropic glutamate receptor 2 (mGluR 2). The chemical synthesis, ...