"Who are you?" This question, in its many variations, is almost inevitable in school applications, job interviews or introspective moments. We spend years, perhaps our entire lives, unraveling the ...

Once a peptide has been identified that binds with high affinity and specificity to an antibody antigen binding fragment (Fab), crystal structures can be determined that demonstrate intermolecular ...

Harmful infectious organisms are identified as invaders due to their antigens (distinct molecules on their surface). Each antibody produced by your immune system binds to a specific antigen and then ...

some of the antibodies were not binding directly to the HIV viral antigen, but to immune molecules on its surface. "These antibodies actually make no direct contact with the viral protein," says ...

When they carried out the experiments on blood from animals that had received multiple doses of an experimental HIV vaccine, they discovered something surprising: some of the antibodies were not ...

Binding affinity and neutralizing activity were determined using bio-layer interferometry and pseudovirus neutralization assays. Primary docking was performed using ZDOCK (3.0.2) to generate the ...

in the absence of stabilizing antibodies or mutations. The substrate-binding site is located within one half of the molecule and, in the apo state, is obstructed by the transmembrane helix (TM) 4.

Although it is crucial for the success of the therapy, we still know very few details about how the antibodies bind to CD20 and how the subsequent reactions take place,' says Professor Markus ...

"Although it is crucial for the success of the therapy, we still know very few details about how the antibodies bind to CD20 and how the subsequent reactions take place," says Professor Markus ...

Although it is crucial for the success of the therapy, we still know very few details about how the antibodies bind to CD20 and how the subsequent reactions take place." This is now likely to ...