News

Antibodies that recognize lipids: A new path for HIV vaccines and autoimmune disease treatments
Lipids are the fatty molecules that make up cellular membranes, creating a protective barrier that regulates what enters and ...
Yahoo Finance21d
iBio Expands Cardiometabolic and Obesity Pipeline through Licensing of First-in-Class Antibody Targeting Activin E from AstralBio
SAN DIEGO, April 22, 2025 (GLOBE NEWSWIRE) -- Bio, Inc. (Nasdaq: IBIO), an AI-driven innovator of precision antibody therapies, today announced a licensing agreement with AstralBio Inc. for a ...
Medical Xpress22d
How increasing antibody-to-antigen ratio enhances immune cell activation
Fine-tuned by the immune system to latch onto a particular site on a pathogen, Y-shaped antibodies bind to their targets with their arms. Meanwhile, the Fc region (or "stem") of the antibody ...
C&EN24d
Oriented Surface Immobilization of Antibodies Using Enzyme-Mediated Site-Specific Biotinylation for Enhanced Antigen-Binding Capacity
The purified antibody was characterized for conjugation specificity and efficiency and used in a functional antigen-binding assay. To quantify the amount of biotinylation on the rat anti-HRP ...
eLife28d
Structure-Guided Loop Grafting Improves Expression and Stability of Influenza Neuraminidase for Vaccine Development
Oseltamivir is shown in red in the sialic acid receptor binding site ... be applied to other antigens. ExpiCHO (Chinese hamster ovary) cells (Thermo Fisher) were used for the production of NA proteins ...
Frontiers29d
The role of complement in the immunopathogenesis of acetylcholine receptor antibody-positive generalized myasthenia gravis: bystander or key player?
In antiacetylcholine receptor (AChR) antibody-positive (Ab+ ... while downregulating pathways associated with antigen binding. In addition, eculizumab reduced leukotriene production, possibly due to ...