The amyloidogenic pathway releases Aβ from C99 peptide, as well as sAPPβ and AICD through cleavage by β- and γ-secretases. (B) Alzheimer's disease. Reduced metal reuptake, potentially through ...

We review the contribution of research in brain volume and of APP to the anabolic hypothesis, and relate APP to other proteins and pathways that have already ... the APP intracellular domain (AICD) ...

2014; Kamat et al., 2016; Cai and Tammineni, 2017). Changes in neuronal activity/signaling in AD can promote the β-amyloidogenic pathway of amyloid precursor protein (APP) processing, leading to ...

Digital technologies and AI are disrupting the way people live, work, and learn. At the same time, education systems need to become both a rapid producer and an avid consumer of digital and data ...

MANILA, Philippines — A bill to allow graduating junior high school students to pick alternative education pathways has been approved on third and final reading by the House of Representatives ...

Overall, digital pathways in education and skills development can be seen as the interplay of two dimensions: (1) depth of digital transitions, the extent to which public policy efforts take a ...

In the passive avoidance test, at the learning trial (day 0), mice of all groups entered the dark compartment, and there were no significant differences among the animals. However, in the testing ...

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