sAPPα is a secreted peptide produced from APP processing along the "non-amyloidogenic" pathway. Meta-analysis did not show a statistically significant difference in the levels of sAPPα in the plasma ...
Figure 1: The pathway of TTR denaturation and amyloid ... and maps out the core of TTR that remains unaltered even under amyloidogenic conditions (Fig. 3). Amyloidogenic conditions thus appear ...
Experiments revealed that nanoparticles within PM2.5 amplify pro-amyloidogenic processing in neural cells, providing a potential pathway for how air pollution contributes to Alzheimer’s disease.