sAPPα is a secreted peptide produced from APP processing along the "non-amyloidogenic" pathway. Meta-analysis did not show a statistically significant difference in the levels of sAPPα in the plasma ...
Figure 1: The pathway of TTR denaturation and amyloid ... and maps out the core of TTR that remains unaltered even under amyloidogenic conditions (Fig. 3). Amyloidogenic conditions thus appear ...
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Study reveals air pollution plays a major role in cognitive declineExperiments revealed that nanoparticles within PM2.5 amplify pro-amyloidogenic processing in neural cells, providing a potential pathway for how air pollution contributes to Alzheimer’s disease.
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