Multiple signaling pathways are engaged by the type I and II IFN receptors, but their specific roles and possible coordination in the generation of IFN-mediated biological responses remain unknown. We ...

Consistent with previously published work suggesting that S6K is the principal downstream signal affected ... in which rapamycin treatment resulted in a dramatic inhibition of phosphorylation of S6 ...

Po opublikowaniu filmiku z napaści na drodze zatrzymany został Jacek Z., sołtys Kątów Rybackich na Mierzei Wiślanej. "W pełni potępiamy zachowania, których granice zostały przekroczone" - skomentował ...

Samsung‘s Galaxy S series made its debut on June 4, 2010, and since then it’s become the phone line most people think of when Android is mentioned. Not all phones are created equal though, so ...

The Galaxy Tab S6 Lite is a new addition to Samsung's tablet lineup. As its name suggests, this is a less expensive version of the Samsung Galaxy Tab S6, which I reviewed late last year. The Galaxy ...

This valuable study identifies a protein called adenosine deaminase-related growth factor (ADGF) as a key regulator of tip formation in the slime mold Dictyostelium discoideum. The authors ...

Roughly six months ago, the company launched the Galaxy S6 and Galaxy S6 Edge, which were in such high demand that Samsung had trouble keeping up. To meet the voracious appetite of consumers, Samsung ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. m 6 A RNA modification has been linked to ...

Objective The authors explored differentially expressed circRNAs in Acute Ischemic Stroke (AIS) and revealed the role and potential downstream molecular mechanisms of circLOC375190. Methods ...

Methods and results Target validation assays showed significant expression of phosphorylated ribosomal protein S6 (pS6), a downstream mediator of ... B and dendritic cells (DCs) and AKT activation ...