T cell receptor (TCR) sequencing, to identify clonotypes shared between blood and synovial fluid; (ii) FOXP3 Treg cell-specific demethylated region DNA methylation assays, to investigate their ...

First, GzmA level is significantly elevated in plasma and synovial fluid and can degrade ECM proteins ... may inhibit proinflammatory cytokine production and abnormal autoimmune T cell differentiation ...

Moreover, joint surface injury by medial parapatellar arthrotomy led to a proliferative response in these Gdf5 lineage cells that clearly contributed to synovial hyperplasia. Most interestingly, ...

Objective The presence of intestinal metaplasia (IM) is a risk factor for gastric cancer. However, it is still controversial whether IM itself is precancerous or paracancerous. Here, we aimed to ...

immune cells, and maturation. According to the tissue and environmental needs fibroblasts develop specific function, (e.g., synovial fluid secretion). Differential expression of the WNT/BMP pathway is ...

Medically reviewed by Anita C. Chandrasekaran, MD Pannus is the abnormal formation of tissues in joints most commonly ...