Protein translocation is an essential, nano-scale dynamic process that facilitates the movement of proteins across cellular ...

There are two reaction pathways for transitions to occur between the energy levels. An ATP-hydrolysis-drive reaction occurs at low temperatures and spontaneous transition happens at high temperatures.

The conserved head structure, the membrane portion and the peripheral stalk (or stalks) together could have formed a translocase that coupled ATP hydrolysis to the transfer of RNA and/or proteins ...

Kinesins contain a conserved motor domain for ATP hydrolysis and microtubule binding, and divergent non-motor domains for family-specific regulatory mechanisms and functions. The regulation of ...

The motor domain contains the catalytic site for ATP hydrolysis and the actin or microtubule-binding site. The neck region acts as a lever arm, amplifying the small conformational changes generated by ...