Research Institute for Light-induced Acceleration System (RILACS), Osaka Metropolitan University, 1-2 Gakuencho, Nakaku, Sakai, Osaka 599-8570, Japan Department of Physics, Graduate School of Science, ...

This paper addresses the important question of quantifying epistasis patterns, which affect the predictability of evolution, by reanalyzing a recently published combinatorial deep mutational scan ...

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.

Researchers use it to measure gene expression and copy number, calculate viral titers, and carry out single-nucleotide ... structure is that of Scorpions, first developed by David Whitcombe at DxS 4.

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.

Using transcriptome analysis alongside SNP (single nucleotide polymorphisms)-GWAS (genome-wide association studies), and SV(structure variant)-GWAS, the researchers identified that the hollow ...

Acute respiratory distress syndrome (ARDS) is present in >10% of all people admitted to critical care and is associated with severe morbidity and mortality. Despite more than half a century since its ...

This short manuscript uses mutation counts in phylogenies of millions of SARS-CoV-2 genomes to show that mutation rates systematically differ between regions that are paired or unpaired in the ...

When she looked into the details of the papers, including the methods and materials sections, she noticed several mistakes in the nucleotide sequences ... inspired by the structure and function of the ...

While it's known that HD is caused by an abnormal expansion of cytosine, adenine and guanine nucleotide repeats in the DNA of the gene responsible for HD, how this mutation interferes with ...