This paper addresses the important question of quantifying epistasis patterns, which affect the predictability of evolution, by reanalyzing a recently published combinatorial deep mutational scan ...

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.

Acute respiratory distress syndrome (ARDS) is present in >10% of all people admitted to critical care and is associated with severe morbidity and mortality. Despite more than half a century since its ...

This short manuscript uses mutation counts in phylogenies of millions of SARS-CoV-2 genomes to show that mutation rates systematically differ between regions that are paired or unpaired in the ...

DNA (deoxyribonucleic acid), the molecular "blueprint" carrying the genetic instructions that influence the growth, ...

Researchers have uncovered a way to manipulate DNA at the atomic level using electric field gradients to control nitrogen nuclear spins. Their findings suggest that DNA could be used as both a storage ...

Rock and dust samples retrieved by NASA from the asteroid Bennu exhibit some of the chemical building blocks of life, ...

20 devilish questions to test your knowledge of the Shipping Forecast. 25 Years of the 21st Century 25 Years of the 21st Century: 1. The Age of Digital Warfare Matthew and his guests look back at ...