Pregabalin is the pharmacologically active S ... neuropathy is 50 mg three times daily and may be increased to 300 mg daily within one week based on efficacy and tolerability.

Pregabalin 82.5mg, 165mg, 330mg; ext-rel tabs. Pregabalin binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system ...

A statistically significant pain reduction and the 50% pain relief required to calculate the NNT was only achieved by patients receiving either pregabalin 300 or 600 mg/day. These patients also ...