Each of the 20 amino acids has a specific tRNA that binds with it and transfers it to the growing polypeptide chain. tRNAs also act as adapters in the translation of the genetic sequence of mRNA ...

In cells transfer RNA (tRNA) translates genetic information from the encoding messenger RNA (mRNA) for protein synthesis. New results from ultrafast spectroscopy and in-depth theoretical ...

Pre-tRNAs are subject to extensive processing, which involves cleavage, addition, and base modifications as indicated below: The tRNA processing ... Other aspects of pre-mRNA processing include ...

When Daniel Fischer cofounded Tevard Biosciences in 2017, he wasn’t trying to bet on the next hot RNA technology. His interest was more personal. His daughter Natasha has Dravet syndrome, a rare ...

A pastel colored growing graph with a rising rocket. This article is part 2 of a series on next-generation mRNA vaccines. The first installment can be read here. The unprecedented speed with which ...

Lipids formulated with a bioreducible linker form the wall of nanoparticles encapsulating the mRNA of Cas9 plus sgRNA. Upon entering the cell, in vitro or in vivo, the linkers are broken and the ...

Liu Qiang at the University of Science and Technology of China (USTC) reveals the critical role of glutamate tRNA fragments in brain aging and Alzheimer's disease. The study found age-dependent ...