Models based on this structure combined with biochemical data suggested that the protein does not recognize tRNA-like features of the intron as ... are absent from non-splicing bacterial TyrRSs ...

including the excision of an intron by specific endonucleases. In humans, this is catalyzed by the enzyme tRNA splicing endonuclease (TSEN). Although essential to protein production, it was mostly ...

Fungal tRNA Splicing as a Paradigm of RNA Repair – Intron-containing tRNAs are widespread in eukarya; the intron is usually located in the anticodon loop of the pre-tRNA and must be removed precisely ...

This critical function of removing the intron is called splicing -- in essence, a pre-requisite chemical reaction affirming that tRNA can deliver the correct instructions for protein production.

In some tRNAs, this includes a step in which a certain section, known as an intron, is excised. In humans, the tRNA splicing endonuclease (TSEN) performs this task. The enzyme RNA kinase CLP1 ...

Other types of spliceosomes that recognise unusual or mutated intron sequences also exist, known as minor spliceosomes. tRNA splicing is far rarer, though does occur in all three major domains of ...

During splicing, the spliceosome assembles on the pre-mRNA molecule and brings together the donor site at the 5' end of the intron and the acceptor site at the 3' end of the intron. The intron is then ...

alternative splicing, and messenger RNA processing. Transfer RNA-derived fragments (tRFs) are small molecules present in most organisms. tRHs or tRNA halves are generated when certain tRFs are ...

This critical function of removing the intron is called splicing – in essence, a pre-requisite chemical reaction affirming that tRNA can deliver the correct instructions for protein production.