while a current age- and BMI-adjusted threshold for HFpEF rule in had a specificity of only 65%. In the derivation cohort, a rule-out NT-proBNP threshold (less than 50 pg/mL) lower than the ...

or incident heart failure due to AS progression -- over the next 2 years depending on AS severity and adjusted NT-proBNP: Mild AS and normal NT-proBNP: 1.39 per 100 patient-years Mild AS and ...

And if we want to identify them, we need to be cognizant of what NT-proBNP levels can rule in or rule out HFpEF, and which are indeterminate.” The thresholds should be adjusted based on the presence ...

Based on the relative-risk regression analysis, elevated NT-proBNP levels were strongly associated with prevalent AF, with an adjusted prevalence ... including age, sex, medication use, blood ...

The mean age of participants ... risk Among individuals with a NT-proBNP level of ≥125 pg/mL at both visits, there was an increase in incident HF risk (adjusted hazard ratio [HR] 2.40, 95% ...

and/or NT-proBNP (>age-sex-specific 97.5th percentiles). Prediction performance was assessed using AUC in models with and without GLS and NT-proBNP and compared using DeLong's test for IGHG moderate- ...

The median overall NT-proBNP concentration at visit 5 was 124 (64-239) pg/mL. Older age, White race, female sex, lower socioeconomic status, lower body mass index (BMI),cardiovascular ...

Methods: Stored serum samples were analysed for NT-proBNP concentrations of 14 healthy endurance athletes (mean age: 25 (SD 5) years; VO 2peak 67 (SD 6) ml/min/kg), who had been examined previously ...

The mean age was 73 years ... sacubitril/valsartan significantly reduced NT-proBNP compared with individualized medical therapy (adjusted geometric mean ratio = 0.84; 95% CI, 0.8-0.88; P ...