In our structure, this domain forms crystal contacts ... were incubated for 30 min at 25 °C. No nucleotide was added to the mixture. Reaction mixtures were filtered through a 0.22-μm ...

Members of the research community can come to Berkeley Lab's Advanced Light Source (ALS) user facility knowing nothing more than the molecule's nucleotide sequence and get a structure, or they can ...

In CBASS systems, a cGAS/DncV-like nucleotidyltransferase synthesizes cyclic di- or tri-nucleotide second messengers in response to infection, and these molecules activate diverse effectors to mediate ...

Now researchers have used cryo-electron microscopy to solve the first structure of an active form of an RNR. These complicated enzymes consist of two subunits, α and β. In the Escherichia ...