FIZZ1, a protein found in the lungs, increases the number of myofibroblasts in the lungs. Liu et al hypothesized that Notch1, which regulates cell fate in numerous cell types, plays a role in ...

UCLA scientists have found that a protein known as NOTCH1 helps ward off inflammation in the walls of blood vessels, preventing atherosclerosis—the narrowing and hardening of arteries that can ...

"Because of these families, we found that the NOTCH1 protein normally shuts down factors that control bone development, and this may provide clues for understanding why tissues become abnormally ...

However, when miR-34a was overexpressed in TP53-mutated CLL cells, there was no significant change in NOTCH1 protein levels or signaling activity. "Our results indicate that miR-34a reduces NOTCH1 ...

"Because of these families, we found that the NOTCH1 protein normally shuts down factors that control bone development, and this may provide clues for understanding why tissues become abnormally ...