Wnt5a is a representative ligand that activates the β-catenin-independent pathway in Wnt signaling. Although it has been reported that abnormal activation of the Wnt/β-catenin-dependent pathway ...

The canonical Wnt signaling pathway. The left panel (A) demonstrates the activated Wnt signaling cascade, while the right side portrays the inhibited Wnt signaling cascade. Wnt binds to the Fz ...

Genomic analysis from BLASST-1 (Bladder Cancer Signal Seeking Trial) of nivolumab, gemcitabine, and cisplatin in patients with MIBC undergoing cystectomy.

The fact that six of these nine loci harbor genes encoding proteins in the Wnt-signaling pathway suggests that aberrations in this pathway are key to the process of fibromatosis in Dupuytren's ...

Among the pathways originating from ectopic endometrial stromal cells, the non-canonical WNT pathway ... pair involved in this signaling. This helped them identify that ectopic endometrial stromal ...

Canonical Wnt signaling is activated as secreted Wnt ligands bind to the seven-pass transmembrane receptor Frizzled (blue) and the single-pass low-density lipoprotein receptor-related protein (LRP) ...

A new editorial paper titled " Impact of cortactin in cancer progression on Wnt5a/ROR1 signaling pathway" has been published in Oncotarget. Cortactin (also known as EMS1 or CTTN) is expressed ...

The mutations affected WLS protein stability and Wnt signaling. Knock-in mice showed tissue and cell vulnerability consistent with Wnt-signaling intensity and individual and collective functions ...

It has been previously demonstrated that the WNT gene/protein family member WNT5A is down-regulated in leukemia, and low expression of this tumor suppressor has been correlated with disease ...

Scientists from A*STAR's Institute of Medical Biology (IMB) and Stanford University have found strong evidence that Wnt signalling is a crucial component in the maintenance of hair follicle stem ...

Researchers at the University of Illinois, Urbana-Champaign, developed an approach using blue light to activate the Wnt signaling pathway in frog embryos. The pathway plays a wide variety of roles ...