HIV-1 Vif induces a unique and prolonged pseudo-metaphase arrest by disrupting phosphatase feedback regulation at the kinetochore.
The A3F and A3G interaction results in partial protection of A3F from HIV-1LAI Vif-mediated degradation. HIV-1LAI (LAI) and LAI SLQ mutant (SLQM) viruses were used to determine the Vif-mediated ...
After completing her Ph.D. thesis entitled “Investigations concerning the function of the HIV-1 Vif protein: Generation of a cell-culture model system by using selectable, replication-competent HIV-1” ...