In lab studies, the orally active drug has been shown to degrade the VAV1 protein expressed in T- and B- cells. VAV1 is thought to be a signalling protein involved in the production of pro ...
MRT-6160 degrades a protein called VAV1. "Overall, we see this favorable collaboration agreement as additional robust ...
Pursuant to the deal, Novartis will obtain exclusive worldwide rights to develop, manufacture and commercialize MRT-6160 and ...