these tumor-associated neutrophils actually start to work for the tumor rather than against it by suppressing further anti-cancer interventions from the immune system. Now, scientists know how ...

New research published in Cancer Cell suggests that tumour-associated neutrophils can have antitumorigenic ('N1') or protumorigenic ('N2') functions, a plasticity that has been well described for ...

Neutrophils, one of the immune system warriors that were thought to be all the same, turn out to be diverse. Unfortunately, ...

Prior studies in both animals and humans have reported that neutrophils can cross the blood-brain barrier, and although these cells are not typically attracted to glioblastomas, they are recruited at ...

These hormones help the body initiate the inflammatory response and respond to and fight infection, cancer, and other diseases. Changes in neutrophil and lymphocyte levels have been associated ...

[23] The identification of an 'EMT-associated tumor secretome' may not only lead to the identification of molecular markers of tumor EMT, but also to the identification of novel targets for ...

Single-cell RNA sequencing revealed that neutrophils, a type of white blood cell, near the tumor cells also accumulated these lipids. "We found the tumor cells give the lipid droplets to ...

where the cells become tumor-associated macrophages (TAMs). Once believed to be wholly supportive of cancerous growth, these cells also play important roles in protecting against disease. TAMs can ...

Meanwhile, the team discovered that the formation of areas with high concentrations of hydrogen peroxide was hindered if a type of immune cell called the neutrophil was eliminated from cancer tissue.

Tumor-associated macrophages (TAMs) produce factors that promote angiogenesis, remodel tissue and dampen the immune response to tumors. Specific macrophage types contribute to increased metastases ...