Millions of people worldwide are affected by African sleeping sickness, Chagas disease and other life-threatening infections ...

Millions of people worldwide are affected by African sleeping sickness, Chagas disease and other life-threatening infections caused by microscopic ...

Each of the underlying single-celled parasites—Trypanosoma brucei and its relatives—has one flagellum, a whiplike appendage that is essential for moving, infecting hosts and surviving in ...

Using an innovative in vitro model of the blood-brain barrier, Dennis Grab of Johns Hopkins University and his colleagues found that Trypanosoma brucei gambiense requires calcium ions and cysteine ...

More information: Alexander K. Beaver et al, Tissue spaces are reservoirs of antigenic diversity for Trypanosoma brucei, ...

When infected with T. brucei, wildtype mice lost adipose tissue and had higher levels of fatty acids (FFA), a product of lipolysis. Despite preserving fat mass during the infection, ATGL-deficient ...