Lipid nanoparticle platform delivers mRNA to the brain

Get Instant Summarized Text (Gist) The blood-brain barrier, a protective shield for the brain, poses a significant challenge for delivering medications to treat neurological diseases. Recent ...
The blood–brain barrier (BBB) is meant to protect the brain from noxious agents; however, it also significantly hinders the delivery of therapeutics to the brain. Several strategies have been ...
ABL Bio’s first-in-class bispecific antibodies for Parkinson’s disease combine unprecedented blood–brain barrier penetration with a robust mechanism of action for improved therapeutic efficacy.
For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the blood-brain barrier. In research published in Fluids and Barriers of the CNS, ...