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Next-generation tau radiotracers outperform FDA-approved imaging agents in detecting Alzheimer's disease
"Our work represents an important step toward the harmonization of tau tracers," Zimmer said, "and the results might provide insights into initiatives to create a universal scale for tau tracers." ...
Medscape6d
The Challenges of Tau Imaging
Strategies for Developing Tau Imaging Tracers The heterogenous ultrastructural conformations of tau aggregates pose a challenge for radiotracer design. There are several groups working on ...
ALZFORUM1mon
At Human Amyloid Imaging Conference, Plasma Tau Was the Star
Even as this blood-PET work advances, uncertainty around which tau PET tracers are best is still dogging validation efforts. Ratios of phosphorylated tau species in the plasma predict disease stage ...
ALZFORUM1mon
When Tau Wanders Off, Subcortical Axon Firing Goes Mum
Not only is the LC too small to see on most scanners, but all available tau PET tracers have off-target binding to neuromelanin and ferromagnetic materials throughout this region. “Everything we do in ...
EurekAlert!2y
New PET Tracer Identified for Imaging Tau in Alzheimer's Disease Patients (VIDEO)
Dr. Dean F. Wong from Johns Hopkins reports on the identification of a promising second-generation positron emission tomography (PET) tracer for imaging and measuring tau pathology, contributing ...