Not the Same. In amyloid-negative people (left) few tangles accumulate over a decade. In amyloid-positives (right), tangles grow faster in women (red) than men (blue). [Courtesy of Gillian Coughlan, ...

Even as this blood-PET work advances, uncertainty around which tau PET tracers are best is still dogging validation efforts. Ratios of phosphorylated tau species in the plasma predict disease stage ...

And while tau-PET remains a reliable and accurate predictor of tau burden in the brain, the test’s utility is limited by availability, low resolution, high cost, labor and sensitivity.

Tau silencing gene therapy VY1706 robustly reduced tau mRNA levels, with broad distribution, and was well-tolerated in NHP study; IND filing ...

The study’s researchers scanned the brains of older women who have used HT, observing tau accumulation, a hallmark of Alzheimer disease.

"When we look at changes over time, we see that women have faster rates of tau accumulation than men in areas of the brain ...

Pete Stavropoulos; Analyst; Cantor Fitzgerald & Co. Good afternoon and welcome to Voyager Therapeutics fourth-quarter and year-end 2024 financial results conference call. (Operator Instructions) ...

Voyager Therapeutics (VYGR) announced positive topline data from the Company’s single ascending dose, SAD, trial of VY7523, an investigational ...

Participants were between ages 51 and 89 at the beginning of the study. Participants had PET scans for amyloid beta over a ...