Of all the wily ways tumors have to turn back attacks from therapies or the immune system, an immune protein called TGF-beta may be one of the most curious. In healthy tissues, it can trigger pre ...

That was one of the key findings of a new study led by researchers at Memorial Sloan Kettering Cancer Center (MSK): The TGF-beta and RAS signaling pathways work together to spur the spread of cancer ...

Transforming growth factor-beta (TGF-β)/bone morphogenetic protein ... rely on a precise design of cell therapies. So, the structure of BMP and its receptors is of immense interest due to ...

Multi-omics analysis of human kidney PDGFRβ+ mesenchymal cells quantified over 14,000 biomolecules across 8 time points, ...

The study appears online August 23 in the journal Structure. Smads are key proteins in the signaling pathways of the hormones TGF-beta and BMP, which are known to participate in the control of ...

However, the multifunctional cytokine transforming growth factor beta (TGF-β) has a prominent position among ... Current understanding of TGF-βs molecular structure, signaling pathways, role in ...

Led by researchers at Baylor College of Medicine, the team of scientists found that the Transforming Growth Factor beta (TGF-beta) signaling pathway in uterine cells protects against the disease by ...

AVID200 is designed to selectively neutralize TGF-beta 1 & 3 with best-in-class pM potency, thus neutralizing the principal immunosuppressive TGF-beta isoforms. AVID200’s optimal selectivity is ...

The protein in question is known as TGF-beta, a signaling protein that regulates the division, growth and death of cells. As such, it plays major roles in important jobs like wound healing ...

That was one of the key findings of a new study led by researchers at Memorial Sloan Kettering Cancer Center (MSK): The TGF-beta and RAS signaling pathways work together to spur the spread of ...

Led by researchers at Baylor College of Medicine, the team of scientists found that the Transforming Growth Factor beta (TGF-beta) signaling pathway in uterine cells protects against the disease ...