The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...

Grant led a research team that discovered in 2006 that variation within the gene TCF7L2 raised the risk of type 2 diabetes (T2D). Subsequent research has shown that a variant in this gene region ...

Scientists say they have discovered a variant gene that increases the risk of Type 2 diabetes. The TCF7L2 gene is carried by more than one-third of the U.S. population, the New York Times reported.

Scientists found a crucial role for a diabetes-associated gene, called transcription factor 7-like 2 (Tcf7l2), in regulating the response to nicotine in the brain. Tcf712, which regulates the ...

The team found that people with two copies of the mutant TCF7L2 gene were twice as likely to develop type 2 diabetes as people with no copies. The researchers tracked the cases of 2,676 European ...

This study is one of the first studies of the TCF7L2 gene in a very large, representative sample of diverse Hispanic Latinos and was published today in the journal BMC Obesity. "The ...