Statin rechallenge with a different member of the statin class has been studied. [12] The proportion developing myopathy on introduction of other statins among patients with known simvastatin ...

Statin therapy has proven efficacy for reducing the incidence of major adverse clinical events, but when administered in high doses these agents can cause myopathy. A means to identify those at ...

Nevertheless, it would be helpful to predict the likelihood of developing statin myopathy in an individual patient. Genetic predisposition seems to play a large role in this regard; however ...