A collaborative effort between engineers and biologists at the Hong Kong University of Science and Technology (HKUST) has uncovered a neuroprotective mechanism in spinal cord injury (SCI ...

However, this changes after a traumatic spinal cord injury. Now, researchers at the Ohio State University Wexner Medical Center have uncovered that depleting microglia cells prevents abnormal ...

Research in male mice published in JNeurosci demonstrates activation of microglia in the spinal cord is responsible for increased pain sensitivity in response to stress. John Sheridan and ...

Inside the central nervous system (CNS), a region that includes the brain and spinal cord, it is the job of certain cells, called microglia, to clean up that cellular debris. Microglia have ...

In a series of follow-up experiments, the researchers confirmed the role of CHIT1-positive microglia in motor-neuron degeneration. The degenerative effect was seen in both the spinal cord of non ...

More information: Faith H. Brennan et al, Microglia promote maladaptive plasticity in autonomic circuitry after spinal cord ...

Early treatment caused large numbers of microglia to migrate to the site of spinal cord damage but did not alter astrocyte behavior. Later treatment led to a reduced number of microglia at the ...

A key to their investigation was to elucidate the critical involvement of microglia in axonal degeneration post-spinal cord axon injury. Microglia are primary immune cells in the central nervous ...

Scientists have discovered microglia actually squeeze through the spinal boundary, crossing into the peripheral nervous system in response to injury. Inside the body, disease and injury can leave ...

Now, researchers from Ohio State University have published results showing that activation of microglia in the mouse spinal cord is responsible for increased pain sensitivity in response to stress.