R esearchers at University of Tsukuba have developed "tomoseqr"—a new software tool that enables easy estimation of the three-dimensional (3D) spatial distribution of gene expression. Tomoseqr ...

was first described in Cell in 2021 as the first method to analyze gene expression at sub micrometer-scale spatial resolution. To compare, a single human hair ranges from 20 to 200 micrometers in ...

Spontaneous Russell (left) is a Staff Product Manager for Visium Spatial Gene Expression technologies from 10x Genomics (CA, USA). She has spent the last 20 years leading product development and ...

The field of spatial transcriptomics utilizes technologies that map gene expression data to specific cellular locations within tissues. While traditional RNA sequencing methods generate quantitative ...

This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

A new computational approach successfully combines data from parallel gene-expression profiling methods to create spatial maps of a given tissue at single-cell resolution. The resulting maps can ...

Transcriptome-Scale Spatial Gene Expression in the Human Dorsolaterial Prefrontal Cortex from thescientistllc on Vimeo. Differences in pathology and gene expression associated with neuropsychiatric ...

This spatial differentiation may be driven by ... rather than by stable changes in gene expression. As Özel and Desplan point out, the Max Planck study raises a broader challenge in neuronal ...

Flowers grow stems, leaves and petals in a perfect pattern again and again. A new Cornell study shows that even in this ...

Data were preprocessed by filtering out low-quality cells, and gene expression normalization was applied. Machine learning models were trained on the transcriptomic data for spatial aging clocks ...