Hemoglobin has played a central role in the understanding of many biochemical and biophysical principles, as Eaton and colleagues point out on page 351 of this issue of Nature Structural Biology.

The end product was Heme-Chip, a pocket-sized sickle cell diagnostic tool ... "As far as I know, we are the only group in the world working to make hemoglobin electrophoresis a point-of-care service," ...

How do mutations happen, and how do they influence the future of a species? Molecules of sickle-cell hemoglobin stick to one another, forming rigid rods. These rods cause a person's red blood ...

Sickle cell hemoglobin (HbS) behaves like normal hemoglobin when fully oxygenated, but at low oxygen tension the hydrophobic valine residues cause the HbS to polymerize, resulting in gel formation ...

After moving from Sierra Leone to London, guest columnist Richard Bayliss received a proper diagnosis and care plan for his ...