A new review paper titled "Cellular senescence: when growth stimulation meets cell cycle arrest" has been published in Aging. In this review, researcher Mikhail V. Blagosklonny, M.D., Ph.D., from ...

Although it has been suggested for some time that Id is involved in cell cycle regulation, little is known about the molecular mechanism of this control. Recent studies, however, have revealed ...

quiescence (a non-dividing cell that can re-enter the cell cycle) and senescence of skin fibroblasts, a cell type well known for repairing wounds. Using algorithms, they developed a model that ...

Neuronal cell cycle reentry events in the aging brain are more prevalent in neurodegeneration and lead to cellular senescence. PLOS Biology , 2024; 22 (4): e3002559 DOI: 10.1371/journal.pbio ...

Specific cell-cycle checkpoints are in place to preserve ... Panel A shows primary human fibroblasts cultured in vitro and subjected to senescence-associated acidic β-galactosidase staining ...

Scientists at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, have found that gene editing using ...

As the cell division cycle continuously repeats, the telomere regions at the end of each chromosome get shorter, eventually resulting in cellular senescence, which is when the cell loses the ...

These proteins also participate in the development of the mammary gland, which occurs mainly in women during puberty, pregnancy and the menstrual cycle ... senescence to an increase in the stem ...

identified basic relationships of the cell cycle and cellular senescence in the human placenta. The main finding of the study: During pregnancy, the cycle of cell division of placental ...

Caption Summary image of the article. The upper part highlights neuronal cell cycle re-engagement is a stage proceeding neuronal senescence and that their full molecular profiles can now be ...