Schwann cells make myelin in the peripheral nervous system (PNS: nerves) and oligodendrocytes in the central nervous system (CNS: brain and spinal cord). In the PNS, one Schwann cell forms a ...

Oxysterols are a class of molecules derived from cholesterol via oxidation or as byproducts of cholesterol synthesis. Despite ...

Familial dysautonomia (FD) is a rare but fatal disorder primarily affecting the peripheral nervous system. We have demonstrated ... Other iPSC-based models affecting neural crest lineages include ...