Schwann cells make myelin in the peripheral nervous system (PNS: nerves) and oligodendrocytes in the central nervous system (CNS: brain and spinal cord). In the PNS, one Schwann cell forms a ...

This impairs the structural integrity and bending properties of the plasma membrane, compromising the ability of the Schwann cells to 'wrap' around the peripheral nerves, producing a lipid-rich ...

Familial dysautonomia (FD) is a rare but fatal disorder primarily affecting the peripheral nervous system. We have demonstrated ... Other iPSC-based models affecting neural crest lineages include ...