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Nature24y
The SV40 small t-antigen prevents mammary gland differentiation and induces breast cancer formation in transgenic mice; truncated large T-antigen molecules harboring the intact ...
Although there is no indication that the SV40 virus is involved ... comparable to that of the large T-antigen. The T2-antigen lacks the LXCXE pRb-binding domain and thus sequesters only p53 ...
Nature2mon
Autoinhibition by an internal nuclear localization signal revealed by the crystal structure of mammalian importin α
The structure shows a large C-terminal domain containing armadillo repeats ... corresponding to the monopartite NLS of the SV40 large T-antigen (SV40 NLS) have been described 21.