After the 49ers took a 23-3 lead on the opening drive of the second half of Thursday night's game against the Seahawks, the road team was set to kick off. With 10:07 left in the third quarter.

San Francisco 49ers tight end George Kittle catches a touchdown pass from Tampa Bay Buccaneers quarterback Baker Mayfield in the 2025 NFL Pro Bowl flag football game. San Francisco 49ers fullback ...

The San Francisco 49ers have a roster to remodel come April in the NFL Draft. Injuries and age ravaged the 49ers, leading to ...

San Francisco 49ers running back Christian McCaffrey bulldozes his way into the end zone to extend the 49ers' lead to 14-3 over the Seattle Seahawks. Watch the highlights from Super Bowl LIX ...

San Francisco 49ers' quarterback Josh Dobbs pulls the 49ers to within one point of the Arizona Cardinals on a quarterback push play at the goal line. Watch the highlights from Super Bowl LIX ...

If you've been following the 49ers, you know they most likely will draft a defensive lineman in Round 1 this year.

For the last decade, the San Francisco 49ers have become the gold standard of homegrown talent across the NFL. With a handful of All-Pros on both sides of the football, the 49ers created ...

Watch safety Talanoa Hufanga's top highlights during his four seasons with the San Francisco 49ers.

49ers GM John Lynch says they will “honor” Deebo Samuel ’s request for a fresh start. Samuel has been granted permission to seek a trade, and his tenure in San Francisco will end after six ...

The San Francisco 49ers’ first free-agent signing of the week wasn’t exactly a huge splash. The team addressed the tight end position by agreeing to terms with the Jacksonville Jaguars’ Luke ...

SANTA CLARA — Deebo Samuel Sr. found the perfect plot. On third-and-10, with the game tied at 3 midway through the third quarter, he slanted inside Los Angeles Rams cornerback Darious Williams ...