which are also present in the retroviral vector, and as such could possibly lead to homologous recombination. To make a retroviral production system that is free from homologous recombination ...

Integration of retroviral sequences was determined from ... into cells lacking the natural receptor, the conjugate vector system could also become a useful research tool for virology and gene ...

Retroviral vector-mediated gene transfer has been central to the development of gene therapy. Retroviruses have several distinct advantages over other vectors, especially when permanent gene transfer ...

More recently, the Vector Development Laboratory merged with our group, and we have expanded our services to offer AAV, first-generation adenovirus (FGAd), helper-dependent adenovirus (HDAd), ...

Insertional mutagenesis as an adverse effect of retroviral gene therapy Gene therapy for SCID-X1: 5 of 20 children with leukemia correlated with upregulation of an oncogene due to nearby vector ...

off-the-shelf vector platform to combat cancer by activating the patient’s immune system against the breadth of the patient’s own tumor antigens, is presenting data on two non-integrating ...

CD34+ cells were purified from bone marrow with the use of the CliniMACS system. The cells were ... In this trial, in which an SIN γ-retrovirus vector with deletion of strong viral enhancers ...

Koalas infected with the retrovirus have a compromised immune system, which is why chlamydia is such a big problem for them.(Supplied: Currumbin Wildlife Sanctuary) Retroviruses change our DNA ...

A retrovirus is a virus that works by converting ... In this stage, your immune system won't function properly and you may get more infections. People with AIDS are typically expected to live ...