Retinoid X receptor (RXR) belongs to a family of ligand-activated transcription factors that regulate many aspects of metazoan life. A class of nuclear receptors requires RXR as heterodimerization ...

vitamin D 3 receptor and pregnane X receptor, and permissive partners like peroxisome proliferator-activated receptors (PPARs) α, β/δ, and γ, the farnesoid X receptor (FXR) and liver X ...

Retinoid X receptors (RXRs) have been implicated in the control of a variety of physiological processes including cell differentiation, lipid and glucose metabolism and immune responses 1,2,3,4.

The retinoid X receptor (RXR), a member of the nuclear-receptor superfamily, is a common binding partner for a subgroup of other nuclear receptors. The resulting functional complex of one RXR ...

Background: Some retinoid X receptor (RXR) agonists have potential as cancer drugs. Results: Structures of RXR in complex with two different agonists show similar folds. Dynamics analysis reveals ...

whether nuclear retinoic acid receptors (RARs) and retinoid X receptors (RXRs) are differentially expressed in normal and in cancerous human prostate tissues and (2) whether oral fenretinide therapy ...

doi: 10.1016/j.jmb.2008.03.004. Epub 2008 Mar 18. PubMed PMID: 18621389; PubMed Central PMCID: PMC2593103. Retinoid X receptor (RXR) is a ligand dependent nuclear receptor transcription factor ...

A regulator of gene expression, retinoid X receptor (RXR), can boost scavenging cells in their mission to clear the brain of dead cells and debris after a stroke, thus limiting inflammation and ...

Two families of nuclear receptors, retinoic acid receptors (RARs) and retinoid X receptors (RXRs) are present in skin. Sebocyte activity and differentiation in vitro depends on vitamin A and ...

These receptors (bound to DNA as heterodimers with the retinoid X receptor or as homodimers) were classically thought to recruit corepressors in the absence of ligand to mediate transcriptional ...