The final question asks whether you ever develop ulcers or sores on your digits. While the precise cause of Raynaud's disease is still unknown, certain environmental and lifestyle factors are ...

Raynaud’s disease affects up to 10 million people in ... Secondary Raynaud’s can present a higher risk of complications, including ulcers, scarring and, in very rare cases, tissue death ...

This condition is often associated with systemic sclerosis (scleroderma), an autoimmune disease that causes ... A for treating digital ulcers associated with Raynaud's phenomenon, showing ...

Raynaud's disease is a condition that causes parts of your body, like your fingers or toes, to feel cold and numb when you are in cold temperatures or feeling stressed. Raynaud's occurs in 3% to 5 ...

As an orally available inhibitor of endothelin-1, which has been implicated in the pathogenesis of vascular disease ... ulcers, whether bosentan is also effective in those with SSc-related Raynaud ...

Surface Logix Inc. today announced the initiation of a Phase 2a clinical trial for SLx-2101 in patients with secondary Raynaud's disease ... development of digital ulcers. "PDE-5 inhibition ...