Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept ...

Once activated, Ras can do a variety of things ... Signal binding to membrane receptor tyrosine kinases (RTKs) activates an enzyme called a kinase. Learn how kinases initiate a signaling cascade ...

A new small-molecule inhibitor may put the brakes on Ras by inhibiting the deacylation enzyme APT1. Figure 1: Palmostatin B, a newly described inhibitor of the deacylating enzyme APT1, enhances ...

A large population-based cohort study reports that using GLP-1 RAs significantly reduces the risk for cardiovascular events ...