It’s a continuous growth-promoting translocation, [meaning] it can rearrange and stick on to different partners.” York is a thoracic oncologist and associate professor at Vanderbilt-Ingram Cancer ...

Chromosomal rearrangements of the gene encoding ROS1 occur in approximately 1-2 ... as well as ALK translocations. Of the 103 cases, 39 were adenocarcinomas, 39 squamous cell carcinomas, 5 small ...

“We expect NSCLC patients with ROS1 translocations to benefit significantly from the OxOnc Study results. AmoyDx aims to provide our customers with superior and innovative products and services ...

Biocept's circulating tumor cell (CTC)-based assay confirmed detection of a ROS1 gene translocation in a patient diagnosed with non-small cell lung cancer who had previously received chemotherapy ...

Nuvation Bio's Taletrectinib shows promising data in phase 2 trials for ROS1-positive NSCLC, outperforming current market leaders in key metrics like DOR and PFS. Despite a small target market ...

The publication, entitled "Zidesamtinib Selective Targeting of Diverse ROS1 Drug-Resistant Mutations," is published online and can be accessed here: http://doi.org/10 ...

Taletrectinib, a potent, next-generation ROS1 TKI, continued to demonstrate clinically meaningful efficacy outcomes and favorable safety profiles in patients with ROS1 TKI-naïve or crizotinib ...

A Validation Study for the Use of ROS1 Immunohistochemical Staining in Screening for ROS1 Translocations in Lung Cancer, Journal of Thoracic Oncology (2016). DOI: 10.1016/j.jtho.2016.03.019 ...