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Experiments were performed with male Syrian Golden Hamsters (6–8 weeks old, 50–60 g body weight (bw)) in accordance with institutional guidelines after approval of the animal committee of the ...
As part of its GO™ Peptides collection, AnaSpec has introduced a selection of cyclic and non-cyclic RGD peptides. The RGD (Arg-Gly-Asp) tripeptide motif can be found in extracellular matrix (ECM) ...
The team investigated flexible and rigid linking molecules for the filler of their beta-foldamers, focusing on arginylglycylaspartic acid (RGD.) This alpha peptide sequence found in the ...
A discovery could speed up efforts to produce new antibiotics in the fight against antimicrobial resistance. A discovery made by scientists at King's College London could speed up efforts to ...
A Japanese research team has developed a cyclic peptide (a chain of amino acids bonded circularly) that enhances blood-brain barrier (BBB) penetration. By attaching the cyclic peptide to the ...
“We have now succeeded in generating cyclic peptides that bind to a disease target of our choice and can also be administered orally,” said research lead Christian Heinis, PhD. “To this ...
The company is the latest launched to turn cyclic peptide molecules into orally available drugs that could replace injected or intravenous ones. “Macrocycles in their own right are quite amazing ...
Peptides RGD (Arg-Gly-Asp) and NGR (Asn-Gly-Arg) are the most studied peptides for targeting integrin alphavbeta3 and CD13, respectively.
Cyclic peptides, which combine characteristics of both small molecules and proteins, have emerged as significant molecules for regulating protein–protein interactions (PPIs). Recent studies have ...
Cyclic peptides, which combine characteristics of both small molecules and proteins, have emerged as significant molecules for regulating protein–protein interactions (PPIs). Recent studies have ...
In a paper published in the Journal of the American Chemical Society, scientists from the Department of Chemistry share a new, rapid method for making cyclic peptides – an important class of ...
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