The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and ...
Receptor tyrosine kinases function at the beginning of a number of signal transduction cascades, whereas nonreceptor tyrosine kinases and serine/threonine protein kinases function throughout ...
This content introduces the physiological and pathological importance of protein kinases, kinase inhibitors approved for ...
Glycogen synthase kinase 3 (GSK3) was initially described ... Phosphorylation of the residues targeted by GSK3 should affect the function of the protein in a manner that is consistent with ...
Greatwall, a conserved MAST-like kinase with crucial mitotic entry functions, is curiously absent in worms. Here, the single ...
Cystic fibrosis is a life-threatening disease predominantly with respiratory symptoms. Most of the subjects with the disease harbor the F508del variant in the CFTR gene that causes the protein to ...