Despite significant advancements in spinal muscular atrophy (SMA) management, unmet needs persist, especially for patients ...

Progressive muscular atrophy (PMA) is clinically characterized solely by signs of lower motor neuron dysfunction, so patients with this condition are commonly excluded from ALS clinical trials.

A woman who was going through a divorce and had her symptoms mistook for stress went on to be diagnosed with motor neurone ...

DMD was first described by French neurologist Guillaume Benjamin Amand Duchenne in the 1860s. However, until the 1980s, ...

Symptoms include a loss of motor neurons, atrophy of the voluntary muscles of the limbs and trunk, and progressive muscle weakness. Scholar Rock enrolled 156 patients in the trial and used two doses.

Multiple system atrophy (MSA) refers to a group of progressive neurodegenerative disorders that ... and slurred and low-volume speech. Neck and trunk muscle rigidity or weakness may result in abnormal ...

progressive muscular atrophy and progressive bulpar palsy. Blood phosphorylated (p)-tau 181 and p-tau 217 have been proposed as accurate biomarkers of Alzheimer’s disease pathology. Here ...

Nearly six years ago, the Food and Drug Administration approved Zolgensma, a Novartis gene therapy for the fatal neuron-wasting disease spinal muscular atrophy. It heralded a new era of genetic ...

Progressive Muscular Atrophy, Spinal Macular Atrophy Kennedy's disease, and Post-polio Syndrome," said Dr Wendo. Messages or signals from nerve cells in the brain's upper motor neurons are ...

Amino acid balance could play a role in SMA, as a study showed acids able to influence nervous system function were ...